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In the present study the circadian changes which occur in the levels of corticosterone in the brain and plasma in Sprague-Dawley rats are reported. The levels of corticosterone in the brain were found to have a daily trough and crest with timing similar to that observed for the plasma steroid. In addition, the effect of histamine stress on the(More)
In an attempt to elucidate the mechanism of suppression of the plasma corticosterone stress response in the lactating female rats, nonstress levels of corticosterone in plasma and hypothalamus, cerebral cortex, hippocampus and pituitaries were determined in the lactating and nonlactating Sprague-Dawley rats at 1600-1700 hr by the protein binding assay. The(More)
An analysis of 168 plasma samples from intact rats, one to 35 days of age, was performed using both brief and specific fluorometric procedures. The amount of fluorescence produced by the brief procedure which could be attributed to corticosterone ranged from a maximum of 72% to a minimum of 16% of the total fluorescence value. Corticosterone represented 50%(More)
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