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The Type I restriction-modification enzyme EcoR124I is an archetypical helicase-based dsDNA translocase that moves unidirectionally along the 3'-5' strand of intact duplex DNA. Using a combination of ensemble and single-molecule measurements, we provide estimates of two physicochemical constants that are fundamental to a full description of motor protein(More)
Simulation tools are more and more used during the development and optimization of ultrasonic inspection techniques. Their advantages are clear. They give additional insight in the performance of an inspection technique at low cost. Furthermore, they overcome practical limitations like availability of transducers and test blocks during the design of new(More)
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