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OBJECTIVES To test the hypothesis that exercise training (ET) improves exercise capacity and other clinical outcomes in older persons with heart failure with reduced ejection fraction (HfrEF). DESIGN Randomized, controlled, single-blind trial. SETTING Outpatient cardiac rehabilitation program. PARTICIPANTS Fifty-nine patients aged 60 and older with(More)
,4bstme—A pmeedurefor sequentiaffy eatirnating the parameters and orders of mixed autoregmsive moving-average signaf modefs from tirne-serfes data is presented. Iderrtfffftion ia performed by first fderstffying a purely asrtoregmwive aignaf model. Tire parametem and orders of tbe mixed autoregmsaive moving-average proeeaa are then gfven from tbe solutton of(More)
BACKGROUND Exercise intolerance is the primary symptom in older patients with heart failure and preserved ejection fraction (HFPEF); however, little is known regarding its mechanisms and therapy. METHODS AND RESULTS Seventy-one stable elderly (70+/-1 years) patients (80% women) with compensated HFPEF and controlled blood pressure were randomized into a(More)
BACKGROUND Physical activity (PA) has been shown to benefit glucose tolerance. Walking is a convenient low-impact mode of PA and is reported to be the most commonly performed activity for those with diabetes. The purpose of this study was to determine whether a recommendation to accumulate 10,000 steps/day for 8 weeks was effective at improving glucose(More)
Heart failure with a preserved ejection fraction (HFpEF) is the dominant form of heart failure in the older population. The primary chronic symptom in HFpEF is severe exercise intolerance; however, its pathophysiology and therapy are not well understood. We tested the hypothesis that older patients with HFpEF have increased arterial stiffness beyond what(More)
This paper develops the adaptive disturbance estimate feedback schemes of a companion paper for enhancing the performance of controllers designed by off-line techniques. The developments are based on the parametrization theory for the class of all stabilizing controllers for a nominal plant, and the dual class of plants stabilized by a nominal controller.(More)
SUMMARY In this paper the techniques of extended Kalman filtering (EKF) and hidden Markov mode! (HMM) signal processing are combined to adaptively demodulate quadrature amplitude-modulated (QAM) signals in noisy fading channels. This HMM approach is particularly suited to signals for which the message symbols are not equally probable, as is the case with(More)