J B Brenowitz

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Since 1978, 5005 patients have had coronary artery bypass operations: 50% had conventional grafts only (group A), 25.1% required one coronary artery endarterectomy (group B), and 24.9% required multiple endarterectomies (group C). Operative mortality and long-term survival were stratified within each group according to the presence of additional risk(More)
A plethora of experimental evidence indicates that allopurinol reduces the formation of cytotoxic free radicals during myocardial ischemia and reperfusion. The purpose of this study was to evaluate the effect of allopurinol on cardiac performance and early mortality after coronary bypass surgery. Allopurinol (n = 89) or placebo (n = 80) was administered to(More)
To determine the risks of performing major surgical procedures on patients with chronic renal failure, the charts of twenty-nine hemodialysis patients who underwent thirty-eight elective and nine emergency operations were reviewed. Preoperative preparation included adequate hemodialysis of the patients, 88 per cent of whom were dialyzed within 24 hours of(More)
Sixteen patients with preoperative pulmonary function testing data placing them in the "prohibitive" range underwent major surgical procedures with one mortality (6 per cent) and three major pulmonary complications (19 per cent). All complications were after pulmonary resections in patients with marked muscular weakness. Patients should not be denied(More)
The long-term survival of 6,181 consecutive patients who underwent a coronary bypass operation from 1972 to 1986 was evaluated in relation to certain risk factors: age at the time of operation, sex, preoperative left ventricular function, presence of diffuse coronary artery disease, and previous coronary bypass operation. Advanced age markedly reduced the(More)
Coronary artery endarterectomy and reconstruction are valuable adjuncts to conventional bypass surgery when attempting to revascularize "diffusely" diseased coronary arteries. One hundred forty-four consecutive patients were operated on through February 1986, all of whom required endarterectomy and reconstruction of the left anterior descending, left(More)
Between 1979 and 1986, 65 of 76 patients (86%) (82% men, with a mean age of 58 +/- 8 years) with greater than or equal to 2 previous coronary artery bypass grafting (CABG) operations and symptomatic myocardial ischemia underwent successful percutaneous transluminal coronary angioplasty (PTCA). Sixty-two patients had 2 prior CABG operations, 10 had 3 and 4(More)