J. Alexopoulos

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BACKGROUND Previous research examining the amygdala volumes in major depressive disorder (MDD) has found conflicting evidence for association. Furthermore, few of these studies have examined differences in individuals with an onset during childhood or adolescence. This study examined amygdala volume and its potential association with early onset major(More)
Neuropsychiatric disorders have been demonstrated to manifest shape differences in cortical structures. Labeled Cortical Distance Mapping (LCDM) is a powerful tool in quantifying such morphometric differences and characterizes the morphometry of the laminar cortical mantle of cortical structures. Specifically, LCDM data are distances of labeled gray matter(More)
Electron crystallography is well suited for studying the structure of membrane proteins in their native lipid bilayer environment. This technique relies on electron cryomicroscopy of two-dimensional (2D) crystals, grown generally by reconstitution of purified membrane proteins into proteoliposomes under conditions favoring the formation of well-ordered(More)
Shape differences in cortical structures in the brain can be associated with various neuropsychiatric and neuro-developmental diseases or disorders. Labeled Cortical Distance Map (LCDM) can be a powerful tool to quantize such differences in shapes derived from magnetic resonance images (MRI). This article investigates some aspects of LCDM distances in(More)
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