J. A. Schmitt Ph. D.

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A comparison is made of the results ofTrichophyton mentagrophytes-inoculations onto conventionally-reared and gnotobiotic I.C.R. strain Swiss white mice. It appears that the method of inoculationsite preparation has a decided effect on lesion development, since the mechanical removal of hair with scissors resulted in lesion formation, whereas in the(More)
Results of a preliminary study of the degree of susceptibility of two inbred mouse strains (C 57 B1/6 and DBA2) and the F1 progeny (BDF1) of these lines are reported. The possible significance of our findings are discussed in respect to the published accounts of the influence of the age, physiological response mechanisms, and immunological defense(More)
1. A 0.5 ml inoculum containing 1.4×104 spores and/or mycelial fragments ofAllescheria boydii when injected intraperitoneally, did not cause death in 18–20 g female Swiss mice in 18 days. 2. Focal, pin-point lesions developed in the liver and spleen of mice injected with the stock suspension and the 1:10 dilution of it (2.8×104 and 2.8×103 infective units(More)
Monolayer tissue cultures of canine kidney are demonstrated to by susceptible to invasion by yeast-phaseHistoplasma capsulatum. Primary and secondary tissue cultures of canine kidney show different levels of invasion by the pathogen at 24 hours after inoculation; these differences are interpreted as being related to the number of dividing host cells. By 72(More)
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