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  • J A Nájera
  • 1974
A malaria control field research trial in northern Nigeria was planned with the aid of a computer simulation based on Macdonald's mathematical model of malaria epidemiology. Antimalaria attack was based on a combination of mass drug administration (chloroquine and pyrimethamine) and DDT house spraying. The observed results were at great variance with the(More)
Encouraged by the early success of using dichloro-diphenyl-trichloroethane (DDT) against malaria, the World Health Organization (WHO) embarked on the Global Malaria Eradication Program (GMEP) in 1955. Fourteen years later, the campaign was discontinued when it was recognised that eradication was not achievable with the available means in many areas,(More)
  • J A Najera
  • 1989
Malaria has been one of the main health problems demanding the attention of WHO from the time the Organization was created. This review of the historical record analyses the different approaches to the malaria problem in the past 40 years and shows how WHO tried to fulfil its constitutional mandate. The article exposes the historical roots of the present(More)
Malaria epidemics have recently occurred in many areas of the world, particularly in the irregular fringe, along the limits of distribution of malaria endemicity, whether the limiting factors are temperature (latitude or altitude) or relative humidity (deserts), which were the scene of the major epidemics of the past. A review is made of the current(More)
| This paper addresses the problem of dexterous manipulation of objects using an articulated hand. We describe some geometric reasoning techniques that can be applied to solve active compliance tasks. In this context, ne motion strategies are derived from the positions and forces between the grasped object and the ngers of the hand. Our approach is based in(More)
Malaria, as the most important and widespread of the tropical diseases, is taken as representative of the approaches to their control and the perception of their influence in socioeconomic development. An analysis is presented of the evolution of the main policy orientations for malaria control, since the discovery of mosquito transmission, identifying a(More)
Malathion shows promise as a substitute for chlorinated-hydrocarbon insecticides in the control of malaria whenever the latter are unsuitable because of Anopheles resistance or other reasons. A field trial of malathion was carried out in 1963-64, covering an area of about 500 km(2) with a population of about 26 000, in Masaka District, southern Uganda. All(More)
  • J A Najera
  • 1984
The magnitude of the malaria problem in tropical Africa has been a deterrent to a large-scale control effort as long as the aim was conceived to be only a reduction in transmission. The focus on local priorities brought about by the primary health care approach has resulted in the formulation of a strategy of malaria control that envisages the progressive(More)
A rapid overview is presented of the evolution of the main orientations of malaria control, since the discovery of mosquito transmission. Stated control objectives appear to have oscillated between expectations to eradicate the vector, or at least the disease, and more modest approaches to minimise the effects of the infection. High optimism was raised when(More)