Learn More
A synergistic combination of two next-generation sequencing platforms with a detailed comparative BAC physical contig map provided a cost-effective assembly of the genome sequence of the domestic turkey (Meleagris gallopavo). Heterozygosity of the sequenced source genome allowed discovery of more than 600,000 high quality single nucleotide variants. Despite(More)
The turkey (Meleagris gallopavo) is an important agricultural species and the second largest contributor to the world’s poultry meat production. Genetic improvement is attributed largely to selective breeding programs that rely on highly heritable phenotypic traits, such as body size and breast muscle development. Commercial breeding with small effective(More)
Agricultural animal research has been immensely successful over the past century in developing technology and methodologies that have dramatically enhanced production efficiency of the beef, dairy, swine, poultry, sheep, and aquaculture industries. In the past two decades, molecular biology has changed the face of agricultural animal research, primarily in(More)
Dendritic cells (DC) play a prominent role in the development of T cell-immune responses to antigens and have a key influence over the differentiation of naive T cells into T helper cell type 1 (Th1) or Th2 effector cells. Consequently, there is considerable interest in pharmacological agents that might alter DC function and thereby modulate allergic(More)
Information quality (IQ) problems can have severe consequences in the health care sector. Since its inception, the Canadian Institute for Health Information (CIHI) has recognized the importance of information quality and has implemented a framework designed to evaluate the data quality of the numerous CIHI data holdings. After one year of implementation, a(More)
Avian semen cryopreservation is an invaluable reproductive strategy for conserving desirable genetic traits for commercial poultry production and endangered species conservation. Here we provide the effects of including sialic acid (SA) in the cryodiluent for tom and rooster sperm cryopreservation. Tom and rooster (n=6 males/treatment) semen was incubated(More)
The domestic turkey (Meleagris gallopavo) is an important agricultural species that is largely used as a meat-type bird. Characterizing genetic variation in populations of domesticated species and associating these variation patterns with the evolution, domestication, and selective breeding is critical for understanding the dynamics of genomic change in(More)