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- B R Dunn, J A Hartigan, W L Mikulas
- Applied psychophysiology and biofeedback
- 1999

Electroencephalographic (EEG) recordings from 19 scalp recording sites were used to differentiate among two posited unique forms of mediation, concentration and mindfulness, and a normal relaxation control condition. Analyzes of all traditional frequency bandwidth data (i.e., delta 1-3 Hz; theta, 4-7 Hz; alpha, 8-12 Hz; beta 1, 13-25 Hz; beta 2, 26-32 Hz)… (More)

Suppose that the evolution of a character possessed by a number of current species is modelled as a Markov random eld on an evolutionary tree. Suppose that for each pair of current species we know the joint probability distribution of the pair of characters possessed by that pair of species. We give conditions under which the evolutionary tree can be… (More)

- D Barry, J A Hartigan
- Biometrics
- 1987

The distance between homologous DNA sequences of two species is proposed to be -1/4 ln[det(P)], where P is the conditional probability matrix specifying the proportions of the various nucleotides in the second sequence, corresponding to each of the four nucleotides in the first sequence. A probability model is described which supports this choice of… (More)

- G V Johnson, J A Hartigan
- Journal of Alzheimer's disease : JAD
- 1999

Tau is a microtubule-associated protein that, in a hyperphosphorylated form, comprises the main component of the paired helical filaments and neurofibrillary tangles found in Alzheimer's Disease (AD) brain. It is therefore important to understand the normal functioning and processing of tau protein, and the abnormal posttranslational processing of tau in AD… (More)

- D K Biswas, J A Hartigan, M H Pichler
- Science
- 1984

Bromodeoxyuridine (BrdUrd) treatment of the prolactin nonproducing subclone of GH cells (rat pituitary tumor cells) induces amplification of a 20-kilobase DNA fragment including all of the prolactin gene coding sequences. This amplified DNA segment, which is flanked by two unamplified regions, thus designates a unit of BrdUrd-induced amplified sequence.… (More)

- Alexander I. Barvinok, J. A. Hartigan
- Random Struct. Algorithms
- 2013

We consider the set of all graphs on n labeled vertices with prescribed degrees D = (d 1 ,. .. , d n). For a wide class of tame degree sequences D we prove a computationally efficient asymptotic formula approximating the number of graphs within a relative error which approaches 0 as n grows. As a corollary, we prove that the structure of a random graph with… (More)

- J A Hartigan, G V Johnson
- The Journal of biological chemistry
- 1999

Calcium is a universal intracellular signaling molecule. Through variations in both the amplitude and frequency of intracellular calcium increases, the same calcium ion can elicit different responses. In this report, we investigated the effect of a calcium transient, lasting 2-5 min, on alterations in the phosphorylation state of the cytoskeletal protein,… (More)

- H Xie, J M Litersky, J A Hartigan, R S Jope, G V Johnson
- Brain research
- 1998

The purpose of this study was to examine the modulation of tau phosphorylation mediated by protein kinase A, a kinase with low intrinsic activity, and by the constitutively active glycogen synthase kinase, as well as to examine the subsequent effects on tau-microtubule association in differentiated human SH-SY5Y neuroblastoma cells. Activation of protein… (More)

- J. A. Hartigan
- J. Classification
- 2000

- John Concato, John A Hartigan
- Journal of investigative medicine : the official…
- 2016

A threshold probability value of 'p≤0.05' is commonly used in clinical investigations to indicate statistical significance. To allow clinicians to better understand evidence generated by research studies, this review defines the p value, summarizes the historical origins of the p value approach to hypothesis testing, describes various applications of p≤0.05… (More)