Jürgen Vogt

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OBJECTIVE Mutations in the cardiac ryanodine receptor (RYR2) gene have been reported to cause arrhythmogenic right ventricular cardiomyopathy (ARVC). The molecular mechanisms by which genetic modifications lead to ARVC are still not well understood. METHODS ARVC patients were screened for mutations in the RYR2 gene by denaturing HPLC and DNA sequencing.(More)
[1] An effective and widely used method for removing spurious pits in digital elevation models consists of filling them until they overflow. However, this method sometimes creates large flat regions which in turn pose a problem for the determination of accurate flow directions. In this study, we propose to suppress each pit by creating a descending path(More)
AIMS We studied the effects of cardiac resynchronization therapy (CRT) on global and regional myocardial oxygen consumption (MVO2) and myocardial blood flow (MBF) in non-ischaemic (NICM) and ischaemic dilated cardiomyopathy (ICM). METHODS AND RESULTS Thirty-one NICM and 11 ICM patients, all of them acute responders, were investigated. MVO2 and MBF were(More)
AIMS To investigate the effects of cardiac resynchronization therapy (CRT) on survival in heart failure (HF) patients with permanent atrial fibrillation (AF) and the role of atrio-ventricular junction (AVJ) ablation in these patients. METHODS AND RESULTS Data from 1285 consecutive patients implanted with CRT devices are presented: 1042 patients were in(More)
OBJECTIVE This study aimed to investigate whether adequate treatment of Cheyne-Stokes respiration (CSR) reduces the risk of arrhythmic events in patients with chronic heart failure (CHF). METHODS A cohort of 403 registry patients with CHF (LVEF≤45%, NYHA-class≥2) and implanted cardioverter-defibrillator devices (ICD) was studied. They underwent overnight(More)
AIMS Studies have shown that remote magnetic navigation is safe and effective for ablation of atrial arrhythmias, although optimal outcomes often require frequent manual manipulation of a circular mapping catheter. The Vdrive robotic system ('Vdrive') was designed for remote navigation of circular mapping catheters to enable a fully remote procedure. This(More)
Diatoms are generally known for superior mechanical properties of their mineralised shells. Nevertheless, many copepod crustaceans are able to crush such shells using their mandibles. This ability very likely requires feeding tools with specific material compositions and properties. For mandibles of several copepod species silica-containing parts called(More)
Drought is a normal, recurring feature of climate. The characteristics of this hazard, along with its far-reaching impacts, make its effects on society, economy, and environment difficult to identify and quantify. A national drought watch system has been recommended as a necessary component of drought assessment and management. The National Drought(More)
So beware, those of you to attempt to write philosophy for anyone else to read! (Reimer 2003, x) Despite attempts to establish some sort of international community of music educators who work in the field of philosophy and/or theory of music education, there remains little exchange or discussion between the Anglo-American and the European philosophy of(More)
Remotely sensed Land Surface Temperature (LST) represents a valuable source of data for a simple modelling of the dynamic of soil moisture (SM) over large areas. In this paper we evaluated the capability of LST monthly anomalies, derived from the MOD11C3 standard product, to capture the SM dynamic as modelled over Europe by means of an ensemble of three(More)