Jörn Drappa

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BACKGROUND & AIMS MEDI2070 is a human monoclonal antibody that selectively inhibits interleukin 23 (IL23), a cytokine implicated in the pathogenesis of Crohn's disease (CD). We analyzed its safety and efficacy in treatment of CD in a phase 2a study. METHODS We conducted a double-blind, placebo-controlled study of 119 adults with moderate to severe CD(More)
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