Jörg Hw Distler

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OBJECTIVES To assess whether the discrepancy between the strong antifibrotic effects of tyrosine kinase inhibitors (TKIs) in animal models and the inconsistent results in clinical studies might be related to the activation levels of drug targets. METHODS Skin sections of bleomycin, TSK1, Fra-2 transgenic mice, SSc patients and controls were analysed by(More)
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