József Simon

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Growth hormone (GH) appears to play a major role in a reciprocal axis that has been postulated between the thymus and pituitary glands. Our previous studies showed that thymic structure, as well as T-cell proliferation and IL-2 synthesis, could be restored in aged female Wistar-Furth rats by the implantation of GH3 pituitary adenoma cells. These cells(More)
Beige adipocytes are special cells situated in the white adipose tissue. Beige adipocytes, lacking thermogenic cues, morphologically look quite similar to regular white adipocytes, but with a markedly different response to adrenalin. White adipocytes respond to adrenergic stimuli by enhancing lipolysis, while in beige adipocytes adrenalin induces(More)
The carbonic anhydrase activity in the brain tissue shows a considerable increase with proceeding gliogenesis during the first three postnatal weeks in the rat. The administration of 10 to 30 micrograms corticosterone or 5 to 10 micrograms dexamethasone per g body weight to 3-day old rats produced a marked acceleration in maturation of enzyme activity in(More)
The effects of bilateral electrolytic lesions of the ventromedial hypothalamus (V.M.H.) were examined in male geese. In addition to the known effects (hyperphagia, obesity and liver steatosis), V.M.H. lesions slightly increased plasma insulin level in the fasting and the fed state and largely enhanced insulin levels observed during an oral glucose and amino(More)
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