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Diabetic eye disease remains a major cause of blindness in the world. Laser treatment for proliferative diabetic retinopathy and diabetic macular edema became available more than two decades ago. The outcome of treatment depends on the timing of laser treatment. The laser treatment is optimally delivered when high-risk characteristics have developed in(More)
BACKGROUND We wanted to investigate the relationship between the fecal levels of granulocyte marker protein (GMP) and the presence of aberrant crypt foci (ACF) and colorectal cancer in rats given injections of azoxymethane (AOM) and fed either of two different diets, a basal diet plus 20% corn oil or 20% beef suet, respectively. METHODS The rats received(More)
Ten years after the foundation of a national diabetic eye screening program in 1980, we have established a low prevalence of blindness and partial sight in type 1 and type 2 diabetics in Iceland. We ask whether the screening program is also associated with a low incidence of blindness in diabetics. We now report the results of a prospective study on the(More)
A screening program for diabetic eye disease was established in Iceland in 1980. Approximately 90% of the insulin dependent patients in Iceland undergo annual eye examination and fundus photography and about a fifth of the type 2 diabetic patients. We report on 245 diabetic patients with type 2 diabetes. Any diabetic retinopathy was present in 100 patients(More)
BACKGROUND Fecal calprotectin is elevated in patients with colorectal cancer (CRC). An improved method has been developed. The aim was to evaluate sensitivity and specificity for CRC with the new fecal calprotectin method and to compare the results with those of the original method. METHODS The study comprised 453 subjects including symptomatic CRC(More)
We evaluated a possible therapeutic effect of Ginkgo biloba extract (GBE) on glaucoma patients that may benefit from improvements in ocular blood flow. A Phase I cross-over trial of GBE with placebo control in 11 healthy volunteers (8 women, 3 men: Age; 34 +/- 3 years, mean +/- SE) was performed. Patients were treated with either GBE 40 mg or placebo three(More)
Under a national program established in 1980, the eyes of approximately 90% of the insulin dependent diabetic patients in Iceland have undergone annual eye examination and fundus photography. Laser treatment was given for proliferative retinopathy or diabetic macular edema according to Diabetic Retinopathy Study and Early Treatment Diabetic Retinopathy(More)
Chemical injuries are among the most severe injuries to the eye. Young men are most often affected. Work related injuries are more common than other types of injuries. Immediate treatment is paramount in preventing blindness. In the case of an alkali injury, an opaque cornea and a white edematous conjunctiva indicate a serious injury. In contrast, a clear(More)
AIMS/BACKGROUND Retinal vessel dilatation is a well known phenomenon in diabetes. In this study, the theory of whether excessive changes in diameter and length of retinal vessels occur in the development of diabetic macular oedema was tested, supporting a hypothesis that the development of diabetic macular oedema may be linked to hydrostatic pressure(More)
UNLABELLED Fecal calprotectin (CPT) is elevated in the majority of patients with known colorectal cancer (CRC), but the specificity is not clarified. AIM To evaluate if a CPT test (PhiCal ELISA) was more sensitive than Hemoccult II test in detecting colorectal neoplasia, and to obtain reference values in subjects with normal colonoscopy. To evaluate a(More)