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Antinociceptive and Antioxidant Activities of Phytol In Vivo and In Vitro Models
TLDR
Taken as a whole, these results show the pronounced antinociceptive effects of phytol in the nociception models used, both through its central and peripheral actions, but also its antioxidant properties demonstrated in the in vitro methods used. Expand
Evaluation of acute toxicity of a natural compound (+)-limonene epoxide and its anxiolytic-like action
TLDR
It is suggested that acute administration of the (+)-limonene epoxide exerts an anxiolytic-like effect on mice, and it could serve as a new approach for the treatment anxiety, since it practically does not produce toxic effects. Expand
Anxiolytic-like effects of phytol: Possible involvement of GABAergic transmission
TLDR
It is proposed that phytol interacts with GABAA receptor, probably at the receptor subtypes that mediate benzodiazepines effects, to produce sedative and anxiolytic activities. Expand
Phytol, a Diterpene Alcohol from Chlorophyll, as a Drug against Neglected Tropical Disease Schistosomiasis Mansoni
TLDR
Phytol, a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal fields, possesses promising antischistosomal properties in vitro and in a mouse model of schistosomiasis mansoni, and validates phytol as a promising drug and offers the potential of a new direction for chemotherapy of human schistOSomiasis. Expand
Evaluation of Antioxidant Activity of Phytol Using Non- and Pre-Clinical Models.
TLDR
In vitro and in vivo antioxidant capacity of PHY exerted antioxidant potential in the current non- and preclinical test systems and can be a good candidate for the development of treatments of oxidative stress mediated diseases. Expand
Superoxide dismutase and catalase activities in rat hippocampus pretreated with garcinielliptone FC from Platonia insignis
TLDR
The findings strongly support the hypothesis that GFC isolated from P. insignis has a significant potential to be used as a natural antioxidant agent probably due to the modulation of enzymatic activity of hippocampal SOD. Expand
Pressure ulcer dressings in critical patients: a cost analysis.
TLDR
The role of nurses in creating evidence-based care plans is crucial to improve care management and there was a significant reduction in costs with dressing materials between the initial and final assessments. Expand
Oxidative stress in rat striatum after pilocarpine-induced seizures is diminished by alpha-tocopherol.
TLDR
The hypothesis that oxidative stress occurs in striatum during pilocarpine-induced seizures is supported, indicating that brain damage induced by the oxidative process plays a crucial role in seizures pathogenic consequences, which implies that strong protective effect could be achieved using alpha-tocopherol. Expand
In vitro antioxidant properties of the biflavonoid agathisflavone
TLDR
The antioxidant capacity, reducing potential and inhibition of lipid peroxidation showed by agathisflavone were comparable to that of trolox, which suggests considering this biflavonoid for the use in the prevention and/or treatment of diseases precipitated by oxidative stress. Expand
Perillyl Alcohol: Antinociceptive Effects and Histopathological Analysis in Rodent Brains
Perillyl alcohol (PA) is a natural compound found in essential oils. In this study, the antinociceptive activity of PA was evaluated using acetic acid and formalin tests. The involvement of theExpand
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