We report an autochthonous human case of tickborne encephalitis (TBE) in the Bordeaux area, southwestern France. The patient was a farmer who had severe encephalomyelitis. ELISA and neutralization assay of serum and cerebrospinal fluid established the diagnosis. This potential new endemic focus for TBE virus should be further investigated.
IT IS COMMONLY ACCEPTED that many human diseases are due to the action of environmental factors on individuals with increased susceptibility. Differences in individual susceptibilities can be studied in relation with the antigens coded by the HLA region. Those antigens play an important role in self-recognition processes , and many of them are strongly… (More)