Jérémie Lebrec

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OBJECTIVE Hypertension in diabetes is characterized by abnormal sodium homeostasis, suggesting a particular role of natriuretic peptide pathway. Natriuretic peptides can affect blood pressure (BP) through their plasma concentrations, which are dependent on their receptor activities. We thus assessed the association between nine NPR3 gene polymorphisms and(More)
BACKGROUND Umbilical cord sampling at delivery provides important data on the newborn's metabolism. OBJECTIVE To evaluate the impact of delayed sampling on arterial cord blood lactate values. METHODS Observational study of 168 consecutive deliveries at a tertiary teaching hospital. Arterial cord blood lactate was determined with a test strip method on(More)
Genome-wide association studies (GWAS) continue to gain in popularity. To utilize the wealth of data created more effectively, a variety of methods have recently been proposed to include a priori information (e.g., biologically interpretable sets of genes, candidate gene information, or gene expression) in GWAS analysis. Six contributions to Genetic(More)
OBJECTIVE To evaluate the impact of the duration of pushing efforts on arterial cord blood lactate values. METHODS This was a prospective observational study of 124 consecutive normal vaginal deliveries in a tertiary teaching hospital. Arterial cord blood lactate was determined immediately at birth with a test strip method. Univariate and multivariate(More)
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