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The intensity-based ratiometric FRET (fluorescence resonance energy transfer) method is a powerful technique for following molecular interactions in living cells. Since it is not based on irreversibly destroying the donor or the acceptor fluorophores, the time course of changes in FRET efficiency values can be monitored by this method. ImageJ, a(More)
This paper deals with a retrial queueing system with a finite number of homogeneous sources of calls and a single non-reliable server, which means that the server is subject to random breakdowns depending on whether it is busy or idle. The failure of the server may block or unblock the systems's operations and the service of the interrupted request may be(More)
BACKGROUND The acceptor photobleaching fluorescence resonance energy transfer (FRET) method is widely used for monitoring molecular interactions in cells. This method of FRET, while among those with the simplest mathematics, is robust, self-controlled and independent of fluorophore amounts and ratios. RESULTS AccPbFRET is a user-friendly, efficient ImageJ(More)
In wireless multihop networks each node acts as a relay for the other nodes. Consequently, the distribution of the traffic load has a strong spatial dependence. We consider a dense multihop network where the routes are approximately straight line segments. To this end we introduce the so-called line segment traversing process which defines the movement of(More)
This paper deals with the performance analysis of multiple server retrial queueing systems with a finite number of homogeneous sources of calls, where the heterogeneous servers are subject to random breakdowns and repairs. The requests are serviced according to Random Selection and Fastest Free Server disciplines. The novelty of this investigation is the(More)
This paper is concerned with the performance analysis of finite-source retrial queues with heterogeneous sources operating in random environments. All random variables involved in the model construction are assumed to be exponentially distributed with a parameter depending on the source index and on the state of the corresponding random environment. The(More)
Adoptive transfer of T cells that are gene engineered to express a defined TCR represents a feasible and promising therapy for patients with tumors. However, TCR gene therapy is hindered by the transient presence and effectiveness of transferred T cells, which are anticipated to be improved by adequate T cell costimulation. In this article, we report the(More)
In this paper single server homogeneous finite-source retrial queueing systems are investigated. The server is assumed to be subject to random breakdowns depending on whether it is busy or idle. The failure of the server may block or unblock the system's operations and the service of the interrupted request may be resumed or the call can be transmitted to(More)