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RECENTLY several epidemiological investigations have been reported, showing an association between coffee drinking and cancer of the lower urinary tract produced a strong correlation between coffee consumption and national mortality rates from renal cancer. Arm-strong, Garrod and Doll (1976), however, found no association between coffee drinking and the(More)
This study indicated that there was no significant difference in the incidence of intestinal tumors between germ-free and conventional rats fed a diet containing bracken, suggesting that gut microflora did not play a definite role in bracken tumorigenesis. However, bracken induced exclusively sarcoma but no adenocarcinoma in germ-free rats, whereas it(More)
We examined the modifying effects of freeze-dried whole-leaf Aloe arborescens Miller var. natalensis Berger (designated as 'ALOE') on N-ethyl-N'-nitro-N-nitrosoguanidine (ENNG)-induced duodenal tumorigenesis in C57BL/6 mice. Experiment 1: Male mice were given ENNG in drinking water for the first 4 weeks, and then 10% ALOE in basal diet for 16 weeks.(More)
The effect of bracken on the induction of tumours of the upper alimentary tract by N-propyl-N-nitrosourethan (PNU) was studied in 7-week-old ACI rats. Group I received a solution of 400 pts/10(6) of PNU in their drinking water for 6 weeks; Groups II and III were given PNU as in Group I, and then from 1 week later were fed on diets containing 5 and 30%(More)
It has been known that ileal and urinary bladder tumours were induced by feeding bracken fern to rats Nevertheless, the isolation of a carcinogenic substance present in bracken fern has not yet been successful. Pamukcu et al. (1980) reported that quercetin which is contained in bracken fern was carcinogenic for intestine and urinary bladder in non-inbred(More)
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