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Electrospun nanofibers as a potential controlled-release solid dispersion system for poorly water-soluble drugs.
Soluplus Graft Copolymer: Potential Novel Carrier Polymer in Electrospinning of Nanofibrous Drug Delivery Systems for Wound Therapy
Electrospinning can be used to prepare nanofibrous DDSs of PCL-PVAc-PEG graft copolymer (Soluplus) and to stabilize the amorphous state of a poorly water-soluble PRX.
Development of a novel electrospun nanofibrous delivery system for poorly water-soluble β-sitosterol
A Mini-Review: Needleless Electrospinning of Nanofibers for Pharmaceutical and Biomedical Applications
The objective of the present mini-review article is to elucidate the potential of NLES for designing such novel nanofibrous drug delivery systems and tissue engineering constructs.
This study reports on an orifice-less technique that employs high-intensity focused ultrasound, i.e. ultrasound-enhanced electrospinning, which permitted physical modification of the nanofiber topography at will without using supplemental chemical intervention.
Preparation and characterization of hot-melt extruded polycaprolactone-based filaments intended for 3D-printing of tablets.
Salmon fibrinogen and chitosan scaffold for tissue engineering: in vitro and in vivo evaluation
- Ivo Laidmäe, K. Ērglis, A. Ceb̅ers, P. Janmey, R. Uibo
- Biology, MedicineJournal of Materials Science: Materials in…
- 30 November 2018
Wound healing was more effective using the fibrinogen-chitosan scaffold than in untreated wounds, and could be applicable in various medical purposes including surgery, tissue regeneration, burns, traumatic injuries, and 3D cell culture platforms.
Antibacterial Porous Electrospun Fibers as Skin Scaffolds for Wound Healing Applications
It is shown that pores on single fibers within an electrospun scaffold, in addition to nano- and microscale diameter of the fibers, change the living cell–fiber interactions affecting the antibiofilm efficacy and biocompatibility of the scaffolds for the local treatment of wounds.
Interactions between Chloramphenicol, Carrier Polymers, and Bacteria-Implications for Designing Electrospun Drug Delivery Systems Countering Wound Infection.
- Liis Preem, M. Mahmoudzadeh, K. Kogermann
- Materials Science, BiologyMolecular pharmaceutics
- 16 November 2017
Electrospun chloramphenicol (CAM)-loaded polycaprolactone (PCL) and PCL/poly(ethylene oxide) (PEO) fiber mats were electrospun and characterized in terms of morphology, drug distribution, physicochemical properties, drug release, swelling, cytotoxicity, and antibacterial activity.