Ivo Casagranda

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AIM An implantable loop recorder (ILR) is indicated in patients with unexplained syncope after complete conventional work-up. Data from the literature imply that, in clinical practice, the ILR is underused. The aim of the study was to verify if there is any discrepancy between the use of ILRs in clinical practice and the potential indications based on the(More)
We report the results of a phase III trial in which we compared 5-fluorouracil (5-FU) to 5-FU and folinic acid (FA) in 150 previously untreated metastatic colon cancer patients. Patients were randomized in the ratio of 1:2 to receive 5-FU (370 mg/m2, i.v., for 5 days) in arm A or equidose 5-FU plus FA (200 mg/m2, i.v., for 5 days) for arm B, each cycle(More)
AIMS Although an organizational model for syncope management facilities was proposed in the 2004 guidelines of the European Society of Cardiology (ESC), its implementation in clinical practice and its effectiveness are largely unknown. METHODS AND RESULTS This prospective study enrolled 941 consecutive patients referred to the Syncope Units of nine(More)
STUDY OBJECTIVES There is limited evidence to guide the emergency department (ED) evaluation and management of syncope. The First International Workshop on Syncope Risk Stratification in the Emergency Department identified key research questions and methodological standards essential to advancing the science of ED-based syncope research. METHODS We(More)
D-dimer testing is currently considered a cornerstone in the diagnostic approach of patients with suspected venous thromboembolism (VTE) across different health-care settings, including the emergency department (ED). Nevertheless, inappropriate or incorrect activities developing throughout the total testing process may substantially impair the clinical(More)
UNLABELLED The purpose of this document is to develop recommendations on the use of the latest generation of cardiac troponins in emergency room settings for the diagnosis of myocardial infarction in patients with suspected acute coronary syndrome (ACS) without persistent ST-segment elevation (NSTE-ACS). The main points which have been addressed reaching a(More)
Giorgio Costantino1*, Benjamin C. Sun2, Franca Barbic3, Ilaria Bossi4, Giovanni Casazza5, Franca Dipaola3, Daniel McDermott6, James Quinn7, Matthew J. Reed8, Robert S. Sheldon9, Monica Solbiati1, Venkatesh Thiruganasambandamoorthy10, Daniel Beach11, Nicolai Bodemer12, Michele Brignole13, Ivo Casagranda14, Attilio Del Rosso15, Piergiorgio Duca5, Greta(More)
OBJECTIVES Few data on the incidence, aetiology, clinical features and management of patients with acute allergic reactions presenting to the Emergency Department are currently available. The aim of the study was to report the annual experience of a single Italian adult Emergency Department about anaphylaxis. PATIENTS AND METHODS This is a retrospective,(More)
The Italian health care system is largely socialized, with priorities and policies established both nationally and regionally. Currently emergency medicine in Italy is practiced mainly by traditional specialists, such as internists and surgeons, and the scope of emergency medicine practice is not as broad as that seen in the United States. However,(More)