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Family and twin studies have supported a strong genetic factor in the etiology of obsessive-compulsive disorder (OCD), although the precise mechanism of inheritance is unclear. Clinical and(More)
these five haplotypes was 0.00072 (w1⁄4 21.27, 5df), of which the most significant overtransmitted haplotype was the most common haplotype ‘TGTCA’ (frequency1⁄4 37%, P1⁄4 0.01). Owing to the lower LD(More)
The human serotonin transporter gene (5-HTT) is a candidate for the pathogenesis of mood disorders, including bipolar disorder (BPD). The 5-HTT gene has a 44-bp insertion/deletion polymorphism within(More)
Several reports have suggested the presence of anticipation in bipolar affective disorder (BPAD). In addition, independent studies using the RED (repeat expansion detection) have shown association(More)