Ivana Šušak

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Despite advances in antiepileptic drug (AED) therapy, about one-third of patients with epilepsy are resistant to drug treatment. Functional impact of polymorphisms in drug-efflux transporter genes may contribute to multidrug resistance theory. Studies on ABCB1 gene gave contradictory results and available data suggest that this polymorphism may not directly(More)
The mechanism of interaction of an external magnetic field with liquid was proposed. The statistical integral and configurational contributions for a free energy, entropy and specific heat for the soliton model of bulk knitted structures in a magnetic field were calculated. It was shown that the concentration of solitons depends on the effect of external(More)
Based on the model of a bulk knitted structure, a possible mechanism of action of an external electromagnetic field on biological systems was proposed. The electromagnetic field affects biological processes through changes in the rates of biochemical reactions in response to changes in the conformational properties of water in the electromagnetic field.
Epilepsy is one of the most common neurologic diseases. Despite improved diagnostic and therapeutic possibilities seizures remain refractory in more than 30% of patients with epilepsy. The aim of this study was to analyze the possible predictive factors for the development of pharmacoresistance in cryptogenic partial complex epilepsy. Patients were divided(More)
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