Ivan Marchenko

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Clinical effectiveness and tolerability of o.d. use of fixed dose combinations of perindopril (4 mg) with indapamide (1.25 mg) (Noliprel forte) and captopril (50 mg) with hydrochlorothiazide (25 mg) (Capozide) were compared in a randomized study on 40 patients with I-II degree high and very high risk hypertension. Study duration was 6 months, number of(More)
Hollow microcapsules with the shell composed of biodegradable polyelectrolytes modified with the maghemite nanoparticles were fabricated by in situ synthesis. The nanoparticles were synthesized from the iron salt and the base directly on the capsule shells prepared by "layer by layer" technique. An average diameter of the capsule was about 6.7 μm while the(More)
1. New iron-containing antibiotics, viridomycins A, B, and C, have been isolated from the actinomyceteActinomyces viridaris. 2. Deferriviridomycin A — the precursor of viridomycin A — possesses the capacity for binding not only iron ions but also cobalt, nickel, and copper ions. The copper, nickel, and cobalt analogs of viridomycin A have been obtained.
The sublethal dose of calcium hypochlorite (CH) of 0.2--0.3 mg/ml active chlorine did not cause, after 5 min, morphological changes in the spores of Bacillus anthracoides which could be detected by phase contrast microscopy, or a decrease in the content of dipicolinic acid (DPA) in the spores. Further cultivation of the spores treated with the sublethal(More)
The content of dipicolinic acid (DPA) was assayed in the spores of Bacillus anthracoides 96 during various stages of its growth. The content of DPA was ca. 10.7 per cent of the dry biomass weight in the seven-day-old culture containing 96 to 99 per cent of the spores in a "starvation" medium. The morphology of the culture was modified, and the content of(More)
Oxygen assimilation by the spore suspensions of Bacillus anthracoides under sterile conditions was continuously registered by means of a modified mass-spectrometry technique using an original reaction vessel. The sensitivity of the technique is 2.10(-2) mcl O2 per 1 mg of dry biomass per hour. The technique made it possible to determine the level of(More)
The respiration rate of spore suspensions of Bacillus anthracoides 96 was assayed by mass spectrometry employing a hermetically sealed reaction vessel constructed for this purpose. The rate of respiration was found to depend on the method of preparing suspensions, the duration of their storage at +4 degrees C, the physiological state of spores, and the(More)