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The ExPASy (the Expert Protein Analysis System) World Wide Web server (http://www.expasy.org), is provided as a service to the life science community by a multidisciplinary team at the Swiss Institute of Bioinformatics (SIB). It provides access to a variety of databases and analytical tools dedicated to proteins and proteomics. ExPASy databases include(More)
In this study, we compared the antimicrobial efficacy of various root canal preparation techniques and instruments in the root canals of 40 human first maxillary premolars extracted for orthodontic reasons. After extirpation of the pulp, teeth were sterilized in an autoclave. Then, the root canals were infected with Enterococcus faecalis suspension and the(More)
BACKGROUND Endothelial cell proliferation, angiogenesis, and increased vascular permeability are among the effects of vascular endothelial growth factor (VEGF) in various organs. However, the effects of VEGF on gingival hemodynamics, especially on venules, have not been thoroughly investigated. This study investigated the acute circulatory effects of VEGF(More)
No data are available on the direct acute vascular effect of dental bonding materials on the dental pulp. This study investigated the effects of the components of a composite resin-bonding system on pulpal vascular diameter. Three groups of 10 male Sprague-Dawley rats (weighing 330 +/- 51 g) were used for this investigation. The first lower incisor of the(More)
Despite great progress in the production of new dental polymers, application of these products is still controversial. The unlined utilization of cytotoxic adhesive materials on pulpal dentin can adversely influence the pulp, leading to alterations in local microcirculation that can be an early sign of pathological changes. In a previous study by the(More)
After crown preparation, exposed and untreated dentinal tubules can result in bacterial penetration into pulp. Treating the exposed dentin involves closing the tubules. Dentin sealers are often applied on a very thin dentin layer that covers the pulp chamber. In these cases, the sealers may have some effect on local micro-circulation through dentin. This(More)
The newly developed self-etching, self-priming all-in-one adhesives are appealing to clinicians because they are simple and efficient to use. These single-application bonding systems contain chemically active compounds that can alter pulpal blood circulation when applied to deep dentin surfaces. Since adequate microcirculation and oxygenation are the basic(More)
No data are available on the direct acute vascular effect of dental bond materials in the dental pulp. The purpose of the present study was to investigate the effect of composite resin bonding systems on the pulpal vascular diameter. Three groups of male Sprague-Dawley rats (weighing 300-490 g), each of 10 animals were used for this investigation. The left(More)
Local application of dental bond materials can cause pulpal vasodilation and hyperemia. Such local hemodynamic changes may be mediated by alterations in the levels of locally generated nitric oxide (NO). In different species systemic administration of NO synthase inhibitors leads to a decrease in pulpal blood flow. In contrast, the local administration of(More)
Experimental stimulation and clinical procedures applied on the crown of the tooth cause vascular reaction in the dental pulp. Laser-Doppler flowmetry is a good method for determining the blood flow of the dental pulp. The aim of these experiments was to study the acute effect of a calcium hydroxide-containing pulp-capping material (Dycal, DeTrey) on blood(More)