Ivan G Arestov

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Antimicrobial activity of a tryptic casein hydrolysate (TCH), its mode of antimicrobial action and its efficacy in treatment using a newborn calf colibacillosis model are described. The antimicrobial activity of TCH activated the autolytic system of the microbial cell and was expressed mathematically as the autolysis activation index. TCH stimulated the(More)
The effects of treatment/prophylaxis of newborn calf colibacillosis with tryptic casein hydrolysate (TCH), recently shown to be a novel type of antimicrobial acting through stimulation of the microbial autolytic system, versus an authorized veterinary drug, Fermosorb, were evaluated. Both products showed similar high therapeutic and prophylactic efficacies,(More)
This is the first part of a research report on the in vivo properties of lysosubtilin, a broad-spectrum preparation of lytic enzymes from Bacillus subtilis designed for veterinary medicine. This preparation has both antimicrobial properties and the capacity to compensate for digestive enzyme deficiencies in newborn calves. This study demonstrates its(More)
Lysosubtilin is a broad-spectrum preparation of lytic enzymes from Bacillus subtilis designed for veterinary medicine as an alternative to common antibiotics. The safety of lysosubtilin was studied in acute and subchronic toxicity tests in mice, rabbits, and calves. No sign of toxicosis was observed when lysosubtilin was administered as a single dose per os(More)
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