Iu. F. Pastukhov

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Fasting induces nocturnal hypothermia in pigeons. Slow-wave sleep (SWS) and paradoxical sleep (PS) are associated with reduced heat production in pigeons. The possibility that fasting-induced nocturnal hypothermia is related to increased SWS and PS was examined by comparing body temperature (Tb) and vigilance states when pigeons were fed and fasted. The(More)
Studies of expression of molecular chaperones of the family of Heat Shock Proteins 70 kDa (HSP70) in the mouse and rat brain during sleep deprivation do not answer the question whether the HSP70 produce somnogenic effect. In the present work there are studied effects of exogenous Hsp70 that is known to be able to penetrate into living cells in vitro and to(More)
The songs of adult male zebra finches are termed "directed" and "undirected," depending on the social context in which they occur. Females elicit directed song, whereas undirected song is not addressed to a particular conspecific and even occurs at high levels in social isolation. We tested the hypothesis that the production of undirected song is more(More)
Effects of the inhibitor of the expression of Heat shock proteins 70 kDa (Hsp70), quercetin on seizures and movement disorders induced by N-methyl D-aspartate (NMDA) or pentylenetetrazole in adult rats Wistar were investigated using behavioral methods. It was found that intraperitoneal injection of quercetin 4 hours before intraventricular microinjection of(More)
76 In the last ten years, the hypotheses that chaperr ones of the HSP70 (Heat Shock Protein 70 kDa) famm ily play an important role in the biosynthesis of proo teins and other macromolecules and in sleep recovery dominate in the literature [1–3]. These hypothesis are insufficiently substantiated due to the use of stress models, in which a large number of(More)
Effects of thermal preconditioning universal recognized method of increase in concentration of inducible Heat shock protein 70 kDa (Hsp70i) on characteristics of convulsive activity in Krushinskii-Molodkina (KM) rats with inheritable audiogenic epilepsy were studied. For the first time, it was found that short-term thermal preconditioning (41 degrees C(More)
By using electrophysiological methods, it has been established that muscarinic (M-) cholinergic mechanisms of the ventrolateral preoptic area (VLPA) of pigeon hypothalamus participate in maintenance of wakefulness, whereas nicotinic (N-) mechanisms--in maintenance of the slow-wave sleep. Activation of the VLPA M-cholinergic receptors has been found to be(More)
Data obtained for the last 12 years and modern hypotheses on key function of sleep and the role of Heat Shock Protein 70 kDa (HSP70) molecular chaperones family in sleep modulation are insufficient to determine assotiation of sleep quantity to the level of chaperones in the basic "center" of sleep in the ventrolateral preoptic area (VLPA) of the(More)