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Freshwater fishes that have been isolated by artificial dams have become models for studying the effects of recent barriers on genetic variation and population differentiation. In this study, we examined the genetic structure of 11 populations of white-spotted charr (Salvelinus leucomaenis) by using polymorphic microsatellite loci. Reduced genetic(More)
Isolation by distance is usually tested by the correlation of genetic and geographic distances separating all pairwise populations' combinations. However, this method can be significantly biased by only a few highly diverged populations and lose the information of individual population. To detect outlier populations and investigate the relative strengths of(More)
The white-spotted charr (Salvelinus leucomaenis) is a coldwater-adapted fish distributed in far-eastern Asia. To assess phylogeographic patterns of this species over most of its range in the Japanese archipelago and Sakhalin Island, Russia, we examined nucleotide sequences of the mitochondrial DNA (mtDNA) cytochrome b region (557 bp) in 141 individuals from(More)
Salmonid fishes exhibit high levels of population differentiation. In particular, the brown trout (Salmo trutta L.) demonstrates complex within river drainage genetic structure. Increasingly, these patterns can be related to the underlying evolutionary models, of which three scenarios (member-vagrant hypothesis, metapopulation model and panmixia) facilitate(More)
Introductions of non-native species have caused various negative impacts on native species and their ecosystems. Hybridization is particularly prevalent among closely related species, and can result in displacement, hybrid swarms, or the disruption of a locally adapted gene complex. Although hybridization between native and non-native species is widespread,(More)
Lipoprotein(a) (Lp(a)) was eliminated by LDL-apheresis using a dextran sulfate cellulose column in 3 homozygous and 10 heterozygous familial hypercholesterolemic patients. Immediately after LDL-apheresis by the LA-15 system (continuous LDL apheresis), there were significant reductions in Lp(a) concentrations (28.6 +/- 11.8 mg/dl (mean +/- S.E.) to 9.6 +/-(More)
A novel system has been developed to control granule growth in high shear granulation. The system basically consisted of an image-processing device and a fuzzy control system. A computer-controlled image processor, an air purge unit, a high-energy xenon lighting system and an image probe with a CCD camera comprised the image processing device. A fuzzy(More)
Six homozygous, 10 heterozygous and 8 unaffected subjects in a CETP deficient family confirmed by CETP gene analysis were studied to characterize serum lipoproteins separated by ultracentrifugation, and to examine the relations between CETP levels and lipoprotein lipid concentration and composition. The serum CETP levels were measured by radioimmunoassay(More)
We investigated the relationship between genetic divergence and demographic dependence. Genetically related groups may consist of the same demographic unit or a single “population,” because high levels of dispersal may synchronize population dynamics. We examined this hypothesis by assessing the levels of synchrony in seven demographic parameters among(More)
Intra-specific genetic diversity is important not only because it influences population persistence and evolutionary potential, but also because it contains past geological, climatic and environmental information. In this paper, we show unusually clear genetic structure of the endangered Japanese crayfish that, as a sedentary species, provides many insights(More)