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In recent years, the introduction of massively parallel sequencing platforms for Next Generation Sequencing (NGS) protocols, able to simultaneously sequence hundred thousand DNA fragments, dramatically changed the landscape of the genetics studies. RNA-Seq for transcriptome studies, Chip-Seq for DNA-proteins interaction, CNV-Seq for large genome nucleotide(More)
Using computer simulations, the finite sample performance of a number of classical and Bayesian wavelet shrinkage estimators for Poisson counts is examined. For the purpose of comparison, a variety of intensity functions, background intensity levels, sample sizes, primary resolution levels, wavelet filters and performance criteria are employed. The results(More)
Two dimensional reduction regression methods to predict a scalar response from a discretized sample path of a continuous time covariate process are presented. The methods take into account the functional nature of the predictor and are both based on appropriate wavelet decompositions. Using such decompositions, we derive prediction methods that are similar(More)
The main goal of the whole transcriptome analysis is to correctly identify all expressed transcripts within a specific cell/tissue - at a particular stage and condition - to determine their structures and to measure their abundances. RNA-seq data promise to allow identification and quantification of transcriptome at unprecedented level of resolution,(More)
—Radiances observed by the Interferometric Monitor for Greenhouse gases sounder have been used to retrieve temperature , water vapor, and ozone profiles. It is shown that the sounder allows us to simultaneously retrieve stable solutions for temperature and water vapor. Once water vapor and temperature have been retrieved, ozone profile may be estimated on(More)