Israel Vijayaraj Muthu Vijayan Enoch

Learn More
A modified cyclodextrin is synthesized as an anthracene derivative of 6-deoxy- 6-aminoethylamino-β-cyclodextrin and characterized using IR, NMR, and mass spectral techniques. The compound acts as a sensor of Pb2+ ions in a pool of several metal ions, by enhancement of fluorescence. The absorption spectrum does not show significant changes on the addition of(More)
Spectral characteristics of 2-amino-7-bromofluorene (2ABF) have been studied in aqueous β-cyclodextrin (β-CDx) solution. Enhancement in the fluorescence intensity of the neutral from of 2ABF was observed due to the formation of 1:1 complex with β-CDx. The formation of this complex was confirmed by time-resolved fluorescence spectroscopy. The ground state pK(More)
This work deals with the synthesis of 6-methyl-3-[(4'-methylphenyl)imino]methyl-4H-chromen-4-one (MMPIMC), its binding to β-cyclodextrin, and the influence of the cyclodextrin complexation on the compound's binding to bovine serum albumin (BSA). The 1:2 stoichiometry for the complexation of MMPIMC with β-cyclodextrin is determined with the binding constant(More)
β-cyclodextrin (β-CDx) forms inclusion complexes with 2-aminofluorene (2AF) and 2-amino-9-hydroxyfluorene (2AHF) in different stoichiometries (Guest-host ratio 1:1 and 1:2 respectively) which is discussed on the basis of study by absorption and fluorescence spectroscopy. The ground and the excited state acidity constants for the neutral‒monocation(More)
Inclusion complexation of 2'-hydroxyflavanone (2'HF) with β-cyclodextrin (β-CD) was studied, both in solution phase and as solid inclusion complexes, by UV-visible and fluorescence spectroscopic, scanning electron microscopic and X-ray diffractometric techniques. The interaction of 2'HF with calf thymus DNA (ctDNA) in the presence and the absence of β-CD(More)
The molecular recognition interaction of β-cyclodextrin (β-CDx) was investigated using 2-amino-9-fluorenone (2AFN) by UV, steady-state fluorescence and time-resolved fluorescence measurements in aqueous solution at various pH. The effect of acidity on the ground and excited state equilibria between the neutral and the monocationic forms of 2AFN in water and(More)
The preparation of β-cyclodextrin-conjugated cadmium selenide-silica nanoparticles, the loading of two drugs viz., Atorvastatin and linezolid in the cyclodextrin cavity, and the fluorescence energy transfer between CdSe/SiO2 nanoparticles and the drugs encapsulated in the cyclodextrin cavity are reported in this paper. IR spectroscopy, X-ray diffractometry,(More)
Flavones are biologically active compounds obtained mainly from plant sources. Pharmaceutically important compounds can be delivered to the physiological target by loading them in carriers like cyclodextrins and magnetic nanoparticles. Herein, the binding of 6-methoxyflavone to β-cyclodextrin and DNA is studied using UV-visible absorption and fluorescence(More)
Naringenin-7-O-glucoside [Prunin (Pru)] was isolated from the fruit shell of Bixa orellana L. The binding of Pru with calf thymus DNA (ctDNA) and the influence of cyclomaltoheptaose (β-cyclodextrin, β-CD) on the binding were studied by absorption and fluorescence spectroscopic techniques. The comparison of the binding modes of Pru/β-CD and ctDNA-Pru/β-CD(More)