Ismael Mena

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Diphenylhydantoin (DPH) diminished the therapeutic effects of levodopa both in patients with parkinsonism and in patients with chronic manganese poisoning, as well as the levodopa-dependent dyskinesia for which the former were selected. In patients with Huntington chorea, it enhanced chorea and mental agitation and, thus, failed to conform with the(More)
Exposures to neurotoxic chemicals such as pesticides, glues, solvents, etc. are known to induce neurologic and psychiatric symptomatology. We report on 41 patients--16 young patients (6 males, 10 females, age 34 +/- 8 yrs.) and 25 elderly patients (9 males, 16 females, age 55 +/- 7 yrs). Fifteen of them were exposed to pesticides, and 29 to solvents. They(More)
CONCLUSIONS Bilateral activation of Brodmann area 39 provides functional support for the concept of bilateral cortical activation with auditory stimulation. The observation that when Brodmann area 39 is activated, area 38 of the temporal lobe is simultaneously inhibited (a functional observation that has seemingly not been previously reported) supports the(More)
SUMMARY Autism, Pervasive Development Disorder (PDD), Attention Deficit Hyperactive Disorder (ADHD), and Obsessive and Compulsive Disorder (OCD) involve significant frontal and temporal lobe dysfunction. This conclusion is based on NeuroSPECT work now in progress on children afflicted with these disorders. We have been using NeuroSPECT to image cerebral(More)
CONCLUSIONS Our observations support the concept of bilateral cortical activation with monaural and binaural auditory stimulation. The observation that most of the significantly activated areas were the same with monaural or binaural stimulation suggests that the differences in auditory perception with binaural stimulation are not due to the involvement of(More)
CONCLUSIONS Our observations confirm that musical sensations with no external stimuli, either spontaneous or evoked, occur in normal individuals and that a biological substrate can be demonstrated by brain single photon emission computed tomography (SPECT). OBJECTIVES There are individuals, usually musicians, who are seemingly able to evoke and/or have(More)
The volume of biomedical spatial information available on line increases day by day, which need to be exploited and shared by users in different knowledge areas. NCD 1 kill 38 million people each year and considering the seriousness of the problem globally, there are already underway government strategies to reduce risk factors and early detection and(More)