PURPOSE Wound induced corneal fibrosis can lead to permanent visual impairment. Keratocyte activation and differentiation play a key role in fibrosis, and vimentin, a major structural type III intermediate filament, is a required component of this process. The purpose of our study was to develop a nonviral therapeutic strategy for treating corneal fibrosis… (More)
these spatial limits of the solid state. Presently , one of the most fl ourishing research fi elds and at the same time one of the major challenges faced by contemporary solid state science and technology has been in designing, understanding, and controlling the properties of engineered nanostructures and functional nano-materials (e.g., oxides). [ 1 ] The… (More)
The advent of advanced neuronal interfaces offers great promise for linking brain functions to electronics. A major bottleneck in achieving this is real-time processing of big data that imposes excessive requirements on bandwidth, energy and computation capacity; limiting the overall number of bio-electronic links. Here, we present a novel monitoring system… (More)
Omental lipomas are extremely rare tumors of childhood. We report a case of solitary giant lipoma of the omentum in a child, successfully managed by complete excision, without any recurrence on follow-up study.
Advanced brain-chip interfaces with numerous recording sites bear great potential for investigation of neuroprosthetic applications. The bottleneck towards achieving an efficient bio-electronic link is the real-time processing of neuronal signals, which imposes excessive requirements on bandwidth, energy and computation capacity. Here we present a unique… (More)
Wilms' tumor (WT) is the most common abdominal tumor in children. Many pediatric renal tumors in the past were categorized as WT; however, in recent years, several specific renal tumors have been recognized as distinct pathological entities. The age and clinical presentation of the child and distinctive imaging features may help in reaching a specific… (More)
. Renal Doppler ultrasound, CT angiography, magnetic resonance angiography or venography can be used for the documentation of the degree of left renal vein compression . NCS presented with FMF was first reported in 2009 by Ozcan et al., which was similar to our case . Here, we presume that actually, from the beginning, our patient's proteinuria was… (More)
Angiogenesis plays a key role in tumor growth. Vascular endothelial growth factor (VEGF) is a pro-angiogenic that is involved in tumor angiogenesis. When VEGF binds to membrane-bound vascular endothelial growth factor receptor 2 (mVEGFR2), it promotes angiogenesis. Through alternative polyadenylation, VEGFR2 is also expressed in a soluble form (sVEGFR2).… (More)