Isao Fukuchi

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— This paper describes a method for removing adherent noises from image sequences. In outdoor environments , it is often the case that scenes taken by a camera are deteriorated because of adherent noises such as waterdrops on the surface of the lens-protecting glass of the camera. To solve this problem, our method takes advantage of image sequences captured(More)
It is well established that a pertussis toxin, islet activating protein (IAP), interacts directly with the Ni regulatory protein involved in the receptor-adenylate cyclase system. In this study we investigated the effect of the toxin on the dopaminergic function of the central nervous system in conjunction with the adenylate cyclase system. Direct bilateral(More)
The effects of blockade of muscarinic acetylcholine receptors (mAChR) in rat cerebral cortex on learning and memory were studied by the use of passive and active avoidance tests. Injection of propylbenzilylcholine mustard (PrBCM) into frontal, parietal and occipital cortex decreased mAChR dose dependently, as assessed by 3H-quinuclidinylbenzilate binding(More)
— This paper describes a method for removing adherent noises from image sequences. In outdoor environments, it is often the case that scenes taken by a camera are deteriorated because of adherent noises such as waterdrops on the surface of the lens-protecting glass of the camera. To solve this problem, our method takes advantage of image sequences captured(More)
Pantoyl-gamma-aminobutyric acid (P-GABA) administered i.p. inhibited scopolamine- and atropine-induced locomotor activities in mice, but did not inhibit methamphetamine- and apomorphine-induced locomotor activities. In radiolabeled ligand binding experiments, P-GABA did not inhibit the bindings of [3H]quinuclidinyl benzilate, [3H]spiroperidol and(More)
Effects of taltirelin hydrate (CAS 103300-74-9, TA-0910), a novel thyrotropin-releasing hormone (TRH) analog, on the cerebral monoamine systems, especially the release and turnover of dopamine (DA) in rat brain were compared with those of TRH by intraperitoneal administration. Taltirelin hydrate (1-10 mg/kg) increased the extracellular levels of DA and its(More)
To examine the action of a novel thyrotropin-releasing hormone (TRH) analog, TA-0910 ((-)-N-[(S)-hexahydro-1-methyl-2,6-dioxo-4-pyrimidinylcarbonyl]-L- histidyl-L-prolinamide tetrahydrate), on the cerebral cholinergic systems, the release of acetylcholine (ACh) and choline in freely-moving rats and ACh accumulation in gamma-butyrolactone (GBL, a nerve(More)
Studies were made on the effects of in vivo administration of an "anti-dementia drug", pantoyl-GABA, on choline acetyltransferase (ChAT) activity in mouse brain. Male ICR mice were treated intraperitoneally with 500 mg/kg of pantoyl-GABA, once a day, for various periods. Then they were killed, and the ChAT activities of their cerebral cortex, hippocampus(More)
Mafoprazine, a phenylpiperazine derivative, was neurochemically investigated in rats to determine its action mechanism. The rank order of affinity of mafoprazine for neuronal receptors was D2 greater than or equal to alpha 1 greater than S2 greater than alpha 2 much greater than D1 greater than beta greater than mACh. The affinity of mafoprazine for D2(More)
The interactions of the "antidementia drug" pantoyl-gamma-aminobutyric acid (pantoyl-GABA) with gamma-aminobutyric acid (GABA) receptors were investigated by studies on bindings of radiolabelled ligands in rat brain. Pantoyl-GABA inhibited the binding of [3H]GABA to GABAA receptors and those of [3H]baclofen and [3H]GABA to GABAB receptors in the rat(More)