Isac Alexandre Ferreira-Silva

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The activity of the hypothalamic-pituitary-adrenal axis is modulated by the norepinephrinergic system and, in females, also by the ovarian hormones. We investigated the role of ovarian steroids and the locus coeruleus (LC) on stress-induced corticosterone secretion in female rats. Ovariectomized rats without hormonal replacement (OVX) or treated with(More)
We tested the hypothesis that Locus Coeruleus (LC) inputs to the medial preoptic area (MPOA) and median eminence (ME) are essential for gonadotropin release. Proestrus and ovariectomized (OVX) rats were decapitated at 16:00 h. LC electrolytic lesion was performed at 11:00 h during proestrus and 24h before decapitation in OVX rats. Plasma luteinizing hormone(More)
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