The journals of gerontology. Series A, Biological…
2008
BACKGROUND
To better understand the contribution of frailty to health-related outcomes in elderly persons, it seems valuable to explore data from cohort studies across the world in an attempt to… (More)
PURPOSE
To assess the associations of plasma lutein and zeaxanthin and other carotenoids with the risk of age-related maculopathy (ARM) and cataract in the population-based Pathologies Oculaires… (More)
OBJECTIVES
To determine whether adding cognitive impairment to frailty improves its predictive validity for adverse health outcomes.
DESIGN
Four-year longitudinal study.
SETTING
The French… (More)
OBJECTIVE
To examine the association between caffeine intake, cognitive decline, and incident dementia in a community-based sample of subjects aged 65 years and over.
METHODS
Participants were… (More)
OBJECTIVE
To estimate the percentage reduction in incidence of dementia that would be obtained if specific risk factors were eliminated.
DESIGN
Prospective seven year cohort study.
SETTING… (More)
BACKGROUND
Elevated cortisol levels due to hypothalamic-pituitary-adrenal (HPA) axis stress response have been associated with cognitive impairment. However, the causal relationship between stress… (More)
BACKGROUND
Exposure to light may be an important risk factor for the development of cataracts.
OBJECTIVE
To present the relation of ambient solar radiation and professional and leisure exposures to… (More)
BACKGROUND
Depression may increase the risk of mortality among certain subgroups of older people, but the part played by antidepressants in this association has not been thoroughly explored.
AIMS… (More)
BACKGROUND
Despite the high intake of medications with anticholinergic properties by community-dwelling elderly persons, the effects on cognitive decline and dementia have rarely been evaluated.
… (More)
BACKGROUND
Because brain oxidative stress is a cause of cognitive impairment, selenium, which is an antioxidant, may protect against cognitive decline. The aim of the study was to examine whether… (More)