Isabella Marcomini

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SecA is an essential component of the Sec machinery in bacteria, which is responsible for transporting proteins across the cytoplasmic membrane. Recent work from our laboratory indicates that SecA binds to ribosomes. Here, we used two different approaches to demonstrate that SecA also interacts with nascent polypeptides in vivo and that these polypeptides(More)
Results We showed previously that telomere TG-repeat tract length exerts an epigenetic effect in cis on the activity of nearby subtelomeric replication origins, such that a shortened telomere will replicate earlier [1]. Here we show that deletion of the RIF1 gene, which encodes a telomere-specific Rap1-interacting protein involved in telomere length(More)
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