Isabele Gomes Giori

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The etiology of OCD is largely unknown, but neuroimaging and pharmacological studies suggest that glutamatergic system plays a significant role on OCD development. We genotyped one polymorphism at GRIN2B (rs1019385) by real time Polymerase Chain Reaction in a sample of Brazilian Obsessive-Compulsive patients and healthy controls, and evaluated its influence(More)
Pharmacological data and animal models support the hypothesis that the dopaminergic (DA) system is implicated in obsessive–compulsive disorder (OCD). Therefore, this case–control study assessed whether genetics variations in catechol-O-methyltransferase gene (COMT) could influence susceptibility to OCD and OCD features in a Brazilian sample. A sample of 199(More)
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