Isabel M Remedios

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OBJECTIVES Basic science studies show that the extracellular matrix of adipose tissue, mainly represented by collagen VI, is dysfunctional in obesity and contributes to the development of the metabolic syndrome. We hypothesized in humans that increased collagen VI alpha3-subunit (COL6A3) mRNA is associated with adipose tissue macrophage chemotaxis and(More)
Pityriasis rubra pilaris (PRP) is a rare idiopathic papulosquamous eruption. Few cases of PRP have been reported in association with malignancies. We report a case of an 83-year-old Caucasian male who presented with recalcitrant paraneoplastic PRP as the presenting manifestation of metastatic squamous cell carcinoma with unknown primary. Treatment with(More)
A statistical approach is used to analyze the performance of data allocation optimization techniques in distributed computer systems. This approach is applied to a computer integrated manufacturing (CIM) system with hierarchical control constraints. The performance of some existing general purpose optimization techniques are compared with heuristics(More)
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