Isabel M. Brás Pereira

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ADAM10 (a disintegrin and metalloproteinase 10) is the principal alpha-secretase responsible for the non-amyloidogenic processing of the Alzheimer's disease (AD)-associated amyloid precursor protein (APP). A reciprocal relationship exists between non-amyloidogenic and amyloidogenic APP processing such that impaired ADAM10-mediated proteolysis of the protein(More)
The characterization of several commercial dextrins and the analysis of the potential of dextrin derived hydrogels for biomedical applications were performed in this work. The structural characterization of dextrins allowed the determination of the polymerization and branching degrees, which ranged from 6 to 17 glucose residues and 2 to 13%, respectively.(More)
In this paper, the assessment of curricular internships performed by the chemical engineering students from the last year of first cycle graduation from Instituto Superior de Engenharia do Porto (ISEP) is analysed considering the company supervisor point of view. The objective of this study is to verify if the students are able to integrate the real working(More)
The focus of this case-study is to analyze the impact of a practical work in the learning process of the Fluid Transport Systems course of the Bachelor degree in Chemical Engineering of the Instituto Superior de Engenharia do Porto. The Practical Work is proposed by the responsible teachers and the students are free to choose the application case. The(More)
Secondary immunodeficiences are associated with an increased incidence of infection and malignancy, as well with development of autoimmune disease. Immune system function is altered by many conditions, such as aging, malnutrition and mycobacterial infections. However, the treatment of the primary condition often results in the improvement of the immune(More)
This study explored the relationship between organizational commitment and job satisfaction among workers in family health units. Six family health units in the North of Portugal participated, including 105 health professionals (physicians, nurses, and clinical secretaries). The study used the Portuguese adaptations of the Organizational Commitment Scale by(More)
The present study reports early findings on freshman's perceptions in Electrical/Electronic Engineering courses from four higher education institutions: two Portuguese (Instituto Superior de Engenharia do Porto, ISEP, and Universidade do Minho, UM) and two Brazilian (Instituto Federal de Santa Catarina, IFSC, and Universidade Regional de Blumenau, FURB). (More)
BACKGROUND Patient satisfaction is a complex, multidimensional concept that is difficult to measure. However, there is agreement that understanding the expectations of a patient community or "what is important to them" is an essential consideration. We chose a participatory approach to address patient satisfaction in the context of a primary care teaching(More)
Increasing relevance has been attributed to hydrogels due to their ability to provide an extracellular matrix (ECM)-like environment for cellular adhesion and proliferation, acting as mechanical scaffolds for tissue remodeling or as delivery matrices. In vivo biocompatibility of a hybrid dextrin hydrogel produced from oxidized dextrin and adipic acid(More)
The present study analyses the expectations of chemical engineering students towards their first professional experience before and after doing a curricular internship. This exploratory research applies to students from the last year of first cycle graduation from Instituto Superior de Engenharia do Porto (ISEP) and it is based in the results of two similar(More)
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