Isaac R. Francis

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As multidetector CT has come to play a more central role in medical care and as CT image quality has improved, there has been an increase in the frequency of detecting " incidental findings, " defined as findings that are unrelated to the clinical indication for the imaging examination performed. These " incidentalomas, " as they are also called, often(More)
Hepatocellular carcinoma is the third most common cause of cancer-related death. In the past few years, staging systems have been developed that enable patients to be stratified into treatment algorithms in a multidisciplinary setting. Several of these treatments involve minimally invasive image-guided therapy that can be performed by radiologists.
Sixteen years experience (1974-1989) is recorded with the treatment of 18 patients with retroperitoneal sarcoma. The tumor was palpable in all. Four syndromes could be differentiated in these patients: gastrointestinal, renal, vascular and neurologic. All modern methods of diagnosis were applied: ultrasonography in 12 patients, computer tomography--13,(More)
Primary renal synovial sarcoma (SS) was first described in 2000 by Argani, with only a few subsequent cases being reported in the English literature. Herein, we describe a case of a 52-year-old woman who presented with right flank pain. Magnetic resonance imaging revealed a 6-cm mass in the lower pole of the right kidney. T1 and T2 weighted imaging revealed(More)
PURPOSE To describe the evolving computed tomography (CT) appearances of a cellulose surgical bolster used as a hemostatic agent in patients who undergo laparoscopic partial nephrectomy for renal cell carcinoma. MATERIALS AND METHODS We retrospectively reviewed the follow-up CT studies of 33 patients with stage T1N0M0 renal carcinoma who underwent(More)
Several uncommon primary pancreatic tumors, inflammatory conditions, metastasis to the pancreas and peripancreatic masses can mimic the appearance of pancreatic ductal adenocarcinoma (PDA). Differentiation between these lesions and PDA can be challenging, due to the overlap in imaging features; however, familiarity with their typical imaging features and(More)
With the increasing use of abdominal cross-sectional imaging, incidental adrenal masses are being detected more often. The important clinical question is whether these lesions are benign adenomas or malignant primary or secondary masses. Benign adrenal masses such as lipid-rich adenomas, myelolipomas, adrenal cysts and adrenal haemorrhage have pathognomonic(More)
FDG-PET imaging has significantly altered the workup of the oncologic patient. With the introduction of combined FDG-PET/CT scanners, there has been a dramatic improvement in lesion detection, lesion characterization and accurate lesion localization. As attenuation correction can be attained with the CT images, PET exam times have been dramatically reduced,(More)
Cancers arise from unregulated cellular growth and exhibits a range of pathophysiological characteristics and behaviour. The term " tumour heterogeneity " encompasses a broad range of tumour features that have arisen as a result of different mechanistic processes including stem-cell origin, tumour evolution (linked to genetic mutations and adverse tumour(More)