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OBJECTIVE This paper analyzes the fast and slow mechanisms of adaptation through a study of latencies and amplitudes on ABR recorded at high stimulation rates using the randomized stimulation and averaging (RSA) technique. METHODS The RSA technique allows a separate processing of auditory responses, and is used, in this study, to categorize responses(More)
The recording of auditory brainstem response (ABR) at high stimulation rates is of great interest in audiology. It allows a more accurate diagnosis of certain pathologies at an early stage and the study of different mechanisms of adaptation. This paper proposes a methodology, which we will refer to as randomized stimulation and averaging (RSA) that allows(More)
This paper presents a novel method for automatic selection of regions of interest (ROIs) of functional brain images based on Gaussian mixture models (GMM), which relieves the so-called small size sample problem in the classification of functional brain images for the diagnosis of Alzheimer's disease (AD). In a first step, brain images are preprocessed in(More)
Randomized stimulation and averaging (RSA) allows auditory evoked potentials (AEPs) to be recorded at high stimulation rates. This method does not perform deconvolution and must therefore deal with interference derived from overlapping transient evoked responses. This paper analyzes the effects of this interference on auditory brainstem responses (ABRs) and(More)
Recording auditory evoked responses (AER) is done not only in hospitals and clinics worldwide to detect hearing impairments and estimate hearing thresholds, but also in research centers to understand and model the mechanisms involved in the process of hearing. This paper describes a high-performance, flexible, and inexpensive AER recording system. A full(More)
The masker-probe paradigm is a commonly used technique to reduce stimulus artifact in electrically evoked compound action potential registers. This method takes advantage of the refractory properties of the cochlear nerve, combining the responses to different types of stimulation pulses in order to obtain the biological response free of artifact. In this(More)
Stimulus artifact is one of the main limitations when considering electrically evoked compound action potential for clinical applications. Alternating stimulation (average of recordings obtained with anodic-cathodic and cathodic-anodic bipolar stimulation pulses) is an effective method to reduce stimulus artifact when evoked potentials are recorded. In this(More)
OBJECTIVES The stimulation levels programmed in cochlear implant systems are affected by an evolution since the first switch-on of the processor. This study was designed to evaluate the changes in stimulation levels over time and the relationship between post-implantation physiological changes and with the hearing experience provided by the continuous use(More)
OBJECTIVE In this study, we analyze how electrically evoked compound action potential (ECAP) responses can be used to assess whether electrodes should be activated in the map and to estimate C levels in the Med-El Tempo+ Cochlear Implant Speech Processor. DESIGN ECAP thresholds were measured using the ECAP Recording System of the Pulsar CI implant.(More)
— The recording of auditory brainstem response (ABR) signals is a common measure applied to assess hearing impairments. However, most of the available commercial devices able to record ABR signals can be unaffordable for many medical centers because of their cost and low flexibility. This paper describes a system that allows the recording of high quality(More)
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