Irving D. Kaplan

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A phase I trial was designed to evaluate normal tissue tolerance to neutron capture therapy (NCT); tumor response was also followed as a secondary endpoint. Between July 1996 and May 1999, 24 subjects were entered into a phase I trial evaluating cranial NCT in subjects with primary or metastatic brain tumors. Two subjects were excluded due to a decline in(More)
BACKGROUND Selecting treatment for clinically localized prostate cancer remains an ongoing challenge. Previous decision analyses focused on a hypothetical patient with average preferences, but preferences differ for clinically similar patients, implying that their optimal therapies may also differ. METHODS A decision model was constructed comparing 4(More)
BACKGROUND Little is known regarding how patients select treatment for localized prostate cancer. This study examined determinants of patients' preferences for health states related to prostate cancer, and assessed whether preferences and/or other factors predict treatment choices. METHODS A survey of 167 patients with newly diagnosed localized prostate(More)
BACKGROUND Ipilimumab improves survival in metastatic melanoma patients. This population frequently develops brain metastases, which have been associated with poor survival and are often treated with radiation. Therefore, outcomes following ipilimumab and radiation are of interest, especially given case reports and animal studies suggest combined treatment(More)
Eighteen finger pulp defects were reconstructed using a homodigital dorsal middle phalangeal neurovascular island flap procedure based on a single neurovascular pedicle preserving the length of the finger. All flaps survived and achieved adequate functional and cosmetic results. The mean follow-up time was 22 months. The mean value of static two-point(More)
PURPOSE To assess detailed dosimetry data for prostate and clinical relevant intra- and peri-prostatic structures including neurovascular bundles (NVB), urethra, and penile bulb (PB) from postbrachytherapy computed tomography (CT) versus high resolution contrast enhanced magnetic resonance imaging (HR-CEMRI). MATERIAL AND METHODS Eleven postbrachytherapy(More)
Running Title: " Treatment Choice in Prostate Cancer " Condensed Abstract: Patient preferences for different treatment outcomes related to prostate cancer are shaped by reasonable behavioral influences. However, actual treatment choices bear little relation to these patient preferences, and instead show a strong association with clinician specialty.(More)
The state of American mathematics in the year 1890 was quite bleak. Only two schools offered true graduate education, Both were new, Hopkins having been founded in 1876 and Clark in 1889. When compared to their counterparts in Europe, the courses taught at the vast majority of Amer-ican universities were paltry, the spirit of research almost nonexistent,(More)