Irtaza M Usman

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Diabetic kidney disease (DKD) is associated with oxidative stress and mitochondrial injury. Myo-inositol oxygenase (MIOX), a tubular-specific enzyme, modulates redox imbalance and apoptosis in tubular cells in diabetes, but these mechanisms remain unclear. We investigated the role of MIOX in perturbation of mitochondrial quality control, including(More)
CONTEXT Nodular, intercapillary glomerulosclerotic lesions resembling Kimmelstiel-Wilson nodules commonly observed in diabetic nephropathy can also be seen in patients without any clinical history or evidence of diabetes. OBJECTIVES To discuss the pathobiology of lesions reminiscent of diabetes nephropathy, including light-chain deposition disease,(More)
Purpose: Study was carried out to analyze the key factor that contributes towards worker productivity by determining the correlation, relationship and interactional features between comfort level, environmental factors (noise, heat and lighting) and workstation dimension. The identification of discomfort level was carried out among the operators of three(More)
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