Irma Sottsas

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BACKGROUND Oral squamous cell carcinoma (OSCC) is mainly caused by smoking and alcohol abuse and shows a five-year survival rate of ~50%. We aimed to explore the variation of somatic mitochondrial DNA (mtDNA) mutations in primary oral tumors, recurrences and metastases. METHODS We performed an in-depth validation of mtDNA next-generation sequencing (NGS)(More)
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