Irma Ramirez

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Despite progress in leukemia therapy, most children who experience relapse have a dismal prognosis. New, effective approaches are needed. We conducted a phase 1 study of a novel nucleoside analog, clofarabine, in pediatric patients with refractory and relapsed leukemia. Clofarabine was infused intravenously over 1 hour each day for 5 days. Six dose levels,(More)
The aim of this study was to determine the free amino acid pool in plasma and milk in marginally nourished lactating women. Twenty-eight rural women (age, 23.9+/-5y; weight 50.2+/-4.9 kg; height, 148.2+/-4.8 cm) were studied under metabolic balance conditions. Subjects were divided into 6 groups (5-6 women in each), representing rural mothers postweaning(More)
OBJECTIVE To determine the free amino acid pool in plasma and milk in Mexican rural lactating women. METHODS Twenty-eight women with an age 24 +/- 5.0 (+/- SD) years, weight 50 +/- 4.9 kg and height 148 +/- 4.8 cm were studied under metabolic balance conditions. Subjects were divided into five groups (three groups of lactation at 1st, 3rd and 6th month,(More)
B-cell non-Hodgkin's lymphomas (NHL-B) have been difficult to establish in long-term cell culture using standard techniques. We report the establishment of five representative cell lines from high grade NHL-B using B-cell growth factor (BCGF). The five NHL-B cell lines display the morphologic, immunophenotypic, genotypic, and biologic characteristics of the(More)
Longitudinal studies are the only ones capable of responding to the question of whether cognitive deficits present in schizophrenia follow a stable course and establishing its evolutive relationship with other clinical symptoms of the disease. This article reviews a total of 30 studies published in patients with a first psychotic episode or chronic or(More)
Metabolizable energy (ME) and apparent nitrogen, fat and energy bioavailability from the habitual diet were measured in a group of lactating women from a Mexican rural community. Food intake was estimated in 40 women, age 24 +/- 3 y 3-5 m postpartum, body weight 48.7 +/- 5.4 kg and height 148 +/- 5 cm. Habitual diet was predominantly from vegetable sources(More)
Few experimental data regarding protein requirements of lactating women are available. This study was designed to determine the protein requirement of seven healthy lactating women from a poor Mexican community who were 2-6 mo postpartum and had a mean body mass index of 21.8 +/- 2 kg/m2. Nitrogen balances were performed at intakes of 0.8, 1.0, and 1.2 g.kg(More)