Irma Elashvili

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The intracranial pressure-volume function as determined by brain elasticity is reported in normal dogs. Rapid subarachnoid infusions clearly define an exponential relationship between pressure and volume. An aliquot technique to measure elastance (dP/dV) at multiple intracranial pressures demonstrates a linear relationship between elastance and pressure.(More)
The variable rate lumbar subarachnoid infusion technique allows rapid quantitative study of the cerebrospinal fluid (CSF) compartment. Numerous pressure plateaus are studied in a brief time period with a servo-controlled system. The test determines the difference between rates of CSF absorption and formation as a function of pressure. On-line computer data(More)
BACKGROUND AND AIM The human asialoglycoprotein receptor is a membrane heterooligomer expressed exclusively in hepatocytes. A soluble secreted form, sH2a, arises, not by shedding at the cell surface, but by intracellular cleavage of its membrane-bound precursor, which is encoded by an alternatively spliced form of the receptor H2 subunit. Here we determined(More)
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