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We report rates of regression and associated findings in a population derived group of 255 children aged 9-14 years, participating in a prevalence study of autism spectrum disorders (ASD); 53 with narrowly defined autism, 105 with broader ASD and 97 with non-ASD neurodevelopmental problems, drawn from those with special educational needs within a population(More)
The objective of this study is to investigate whether parentally-reported gastro-intestinal (GI) symptoms are increased in a population-derived sample of children with autism spectrum disorders (ASD) compared to controls. Participants included 132 children with ASD and 81 with special educational needs (SEN) but no ASD, aged 10-14 years plus 82 typically(More)
BACKGROUND Epilepsy occurs in a significant minority of individuals with autism, but few long-term follow-up studies have been reported, so the prevalence, features (type of seizures, age at onset and severity, etc.) and correlates (IQ history of regression, family history) have only partially been identified. AIMS To undertake a long-term follow-up(More)
BACKGROUND Repetitive and stereotyped behaviours are a heterogeneous group of behaviours present in many neuropsychiatric disorders. Despite their core significance in PDD, it is not clear whether there are distinct groups of these behaviours with different specificity to autism. METHODS A two-factor model of the repetitive behaviours, namely(More)
AIMS The Tuberous Sclerosis 2000 Study is the first comprehensive longitudinal study of tuberous sclerosis (TS) and aims to identify factors that determine prognosis. Mode of presentation and findings at initial assessments are reported here. METHODS Children aged 0-16 years newly diagnosed with TS in the UK were evaluated. RESULTS 125 children with TS(More)
is the prototypical form of a group of pervasive developmental disorders that comprise autism, atypical autism, Asperger syndrome and 'other' pervasive developmental disorder. These conditions, as defined in ICD–10, are characterised by qualitative impairments in reciprocal social interaction, qualitative impairments in communication and(More)
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