Irina V Petrisheva

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BACKGROUND Endothelin (ET) -1 was found to participate in the pathogenesis of bronchial asthma. At present, there is no information regarding the role of ET-1 in the pathophysiology of atopic dermatitis (AD). OBJECTIVE We assessed blood ET-1 levels during the exacerbation of AD and during the 4 months postexacerbation period, to assess the relationships(More)
BACKGROUND In atopic dermatitis (AD), monocytes, which accumulate in the inflamed skin, are characterized by a significantly impaired Toll-like receptors (TLR) expression and TLR2-mediated cytokine secretion. However, data on expression of TLR on monocytes of peripheral blood (PB) in AD are not available. OBJECTIVE To investigate TLR2 and TLR4 expression(More)
BACKGROUND There is no currently no information regarding the role of α-defensins in the pathophysiology of atopic dermatitis (AD). AIM To investigate levels of plasma α-defensins at exacerbation and remission of AD, and to assess their association with clinical severity of AD. METHODS Patients with AD during exacerbation were recruited from the(More)
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