To identify loci affecting the electrocardiographic QT interval, a measure of cardiac repolarisation associated with risk of ventricular arrhythmias and sudden cardiac death, we conducted a meta-analysis of three genome-wide association studies (GWAS) including 3,558 subjects from the TwinsUK and BRIGHT cohorts in the UK and the DCCT/EDIC cohort from North… (More)
By 2050, atrial fibrillation (AF) will be present in 2% of the general population and in a far higher proportion of elderly patients. Currently, we are content with rate control and anticoagulation in elderly asymptomatic patients, whereas in younger patients with symptomatic recurrent AF, pulmonary vein isolation is the treatment of choice. However, in a… (More)
Three-dimensional activation properties in a bilayer model of human atria. See figure legend on page iv27.
Our studies deal with fully automatic measurement of heart rate variability (HRV) in short term electrocardiograms. Presently, all existing HRV analysis programs require user intervention for ectopic beat identification, especially of supraventricular ectopic beats (SVE). This makes the HRV measurement in large, e.g. epidemiological studies problematic. In… (More)
The project was funded by the U. S. Agency for International Development (USAID) under the terms of the FRONTIERS Program cooperative agreement number HRN-A-00-98-00012-00 and Population Council Subagreement number AI00.66A " Testing two models of postabortion family planning services to reduce repeat abortions in Russia. " The opinions expressed herein are… (More)
A trial fibrillation (AF) is a global health problem. The condition brings an increased risk of stroke, systemic embolism, and heart failure (HF) and is associated with impaired quality of life, frequent hospitalizations, and mortality. 1 Observational studies have been the main source of information for many years and have defined the clinical… (More)