Irina Madaeva

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We studied the state of the LPO–antioxidant defense system in men aged from 46 to 55 years. The main group included patients with obstructive sleep breathing disorders. The state of the antioxidant defense system was assessed by measuring the blood levels of LPO substrates with conjugated double bonds, conjugated dienes, ketodienes and conjugated trienes,(More)
Menopause is a risk factor for oxidative stress. The aim of our study is to assess antioxidant system parameters (α-tocopherol, retinol, reduced glutathione, total antioxidant activity) in peri- and postmenopausal women. The antioxidant defense activity by estimation of total antioxidant activity, α-tocopherol, retinol, oxidized and reduced glutathione(More)
AIM To evaluate the qualitative characteristics of a sleep in pregnant women in the 3rd term of the physiological pregnancy by a questionnaire survey. MATERIALS AND METHODS We have demonstrated questionnaire survey data of 400 pregnant women (mean age 27.5 +/- 8.2 years) in the 3rd term of pregnancy. Questioning conducted using the scale PSQI (PITTSBURGH(More)
The present study was designed to estimate the effectiveness of non-invasive auxiliary lung ventilation under continuous positive airway pressure (CPAP therapy) and phototherapy applied for the treatment of adolescents presenting with essential arterial hypertension and obstructive sleep apnea/hypopnea. It was shown that CPAP therapy decreased the level of(More)
AIM To assess quantitative characteristics of sleep in perimenopausal women treated with melatonin in a dose of 3 mg during 3 month. MATERIAL AND METHODS A study included 21 perimenopausal women with sleep disorders. Seventeen women completed the study. Insomnia Severity Index (ISI), anamnestic and gynecological examinations, polysomnographic monitoring(More)
The article presents the results of a polysomnographic study with simultaneous monitoring spontaneous nocturnal erections - Nocturnal Penile Tumescences (NPT) in 69 men with age-related androgen deficiency (AAD). Of these, 45 patients were diagnosed with obstructive sleep apnea syndrome (OSAS). In 34 of the 45 patients with OSAS, regimens of non-invasive(More)
Background. There are limited published data in regard to the relationship between obstructive sleep apnea (OSA) and hypertension and neurobehavioral and mental status in adolescence. The aim of our study was to evaluate neurobehavioral patterns and cognitive functions in adolescents with hypertension according to absence or presence of OSA. Methods. This(More)
Comparative analysis of the frequency distributions of genotypes and alleles of 3111T/C Clock gene polymorphism was carried out in climacteric Caucasian women with and without insomnia. Genotype TT is more incident in women with insomnia (55.5% vs. 42.6% in the control). Allele T predominated in the control and study group and its frequency is higher in(More)
AIM To investigate of a lipid peroxidation (LPO) process and the antioxidant defense system (ADS) in peri- and postmenopausal women with insomnia. SUBJECTS AND METHODS 47 perimenopausal women and 71 postmenopausal ones were examined. Each group was divided into 2 subgroups: 1) individuals with insomnia and 2) controls. LPO-ADS spectrophotometric studies(More)